Rams vs. 49ers, Saints vs. Panthers: NFL Week 10 Habits, Picks

Target these two NFC contenders in Week 10.

M Matlani, editor/producer and digital sports editor at Sports Value Startup, returns to the NFL Bettors Guide.

49ERS (+4) pe Rams

The 49ers defended their biggest win of the season, 26-23, 26-23 after overtime.

San Francisco outscored Los Angeles for most of the game, outscoring 20-7 in the third quarter before the Rams rallied in the fourth quarter to force overtime.

This time the 49ers are at home with a field goal.

The Rams are the better team and are holding it, but Day 4 should still be close and can't win this game outright.

Mack Jones has found a home in Kyle Shanahan's system and Brock Purdy could return to this game as well, and Christian McCaffrey could impact the game as a rusher and passer.

Jones completed 33 of 49 passes for 342 yards and two touchdowns in that game, with Kendrick Bourne finding open lanes all night.

Panthers (-4.5) over Saints

Don't look now, but the Panthers are suddenly NFC playoff contenders.

Sunday's loss snapped the Packers' four-game winning streak, and they now head home to welcome Tyler Shoaf for his second career start without Rashid Shahid.

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Putting aside the Bills debacle with Andy Dalton at center, the Panthers are 3-0 at home and are averaging 29 points in their three wins against the Falcons, Dolphins and Cowboys.

The saints, this time, are accidents.They lost all the way this year by less than 12 points, surrendering just 171 rushes to the Herd.

In this case, it doesn't matter if Rico Dowdle is healthy or not.The Panthers are coming off an easy win and could win this game by one or more touchdowns.

2025 record: 5-12-1

Last week: 1-1;49ers(W);Lions (L)